The protamine family of sperm nuclear proteins
نویسندگان
چکیده
منابع مشابه
Involement of an acrosinlike proteinase in the sulfhydryl-induced degradation of rabbit sperm nuclear protamine
Previous studies demonstrated that proteolytic activity is associated with isolated rabbit sperm nuclei and is responsible for the degradation of nuclear protamine that occurs during thiol-induced in vitro decondensation of the nuclei (Zirkin and Chang, 1977; Chang and Zirkin, 1978). In this study, we present the results of experiments designed to characterize this proteolytic activity. Basic p...
متن کاملAn unusual cysteine-containing histone H1-like protein and two protamine-like proteins are the major nuclear proteins of the sperm of the bivalve mollusc Macoma nasuta.
The sperm-specific protamine-like (PL) components PL-I, PL-II, and PL-III from the sperm of the bent-nose clam Macoma nasuta have been isolated and characterized for the first time. These proteins coexist in the sperm nuclei with a small percentage of a full histone complement. All of them have a very similar amino acid composition, following what seems to be the general composition prototype f...
متن کاملChromomycin A3 Staining Indicates Sperm Protamine Deficiency
Chromomycin A3 binds to DNA and Protamine -deficient spermatozoa look bright yellow,whereas normal spermatozoa appear dull yellow.
متن کاملThe amino acid sequence of human sperm protamine P1.
Human sperm protamines have been extracted from spermatozoa pooled from several donors, converted to their S-pyridylethylated derivatives and resolved into two major components, P1 and P2, by Bio-Rex 70 chromatography. Protamine P1 was further purified by Bio-Gel P-10 chromatography and sequenced directly on a gas phase protein sequencer for 43 residues. To complete the sequence, P1 was cleaved...
متن کاملHistone H1 and evolution of sperm nuclear basic proteins.
The Three Main Groups of Sperm Nucleus Basic Proteins (SNBPs) In early studies on the chemical composition of the cell nucleus, it was found that the nucleic acid initially called “nuclein” (1) could form salt-like linkages with two different complexing substances, referred to as “protamine” (2) and “histone” (3). By the end of the nineteenth century, the true protein nature of these complexing...
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ژورنال
عنوان ژورنال: Genome Biology
سال: 2007
ISSN: 1465-6906
DOI: 10.1186/gb-2007-8-9-227